在初级渐进性失言症的三个变体中,对书面语言的自动分析
Sylvia Josephy-Hernandez1, Neguine Rezaii1, Amelia Jones1
1Frontotemporal Disorders Unit, Department of Neurology, Massachusetts General Hospital & Harvard Medical School, Boston, MA 02114, USA.
Brain communications
|August 4, 2023
概括
与对照组相比,初级渐进性失言症 (PPA) 患者的书面语言内容减少. 一个新的程序有效量化了书面语言,揭示了PPA变体和语言模式之间的差异.
科学领域:
- 神经学 神经学
- 语言学的语言学.
- 计算语言学 计算语言学
背景情况:
- 书面沟通缺陷在初级渐进性失言症 (PPA) 中没有得到充分研究.
- 以前的研究经常单独分析PPA变体,缺乏与口语的直接比较.
- 手动分析书面语言是耗时和劳动密集的.
研究的目的:
- 开发和验证一种用于量化书面和口语语言内容单位和总单位的新型程序.
- 为了比较不同类型的PPA (nonfluent,logopenic,semantic) 和控制的书面和口语语言生产.
- 调查书面语言缺陷与PPA严重程度之间的关系.
主要方法:
- 开发一个程序,在语言样本中自动量化内容单位和总单位.
- 分析了来自115名参与者 (对照组和PPA变种) 的西方阿法西亚电池野餐场景的书面和口头描述.
- 计算内容单位对单位比率作为内容密度的度量.
主要成果:
- 开发的程序在识别内容单元方面取得了很高的准确性 (99.7%).
- 与对照组相比,所有PPA变体的书面总单位数量都较少.
- 逻辑开放式和语义变体的书面内容单位比对照组少,而非流动式和语义变体的书面内容单位比对照组高.
- 书面和口头语言的测量在非流利的变体中有显著的相关性,但在logopenic或语义变体中没有.
- 降低PPA的含量单位与更大的失言症和痴呆症严重程度相关.
结论:
- 与健康对照组相比,患有PPA的患者表现出较少的书面内容.
- 非流利和语义的PPA变体表现出对内容的偏好,而不是书面的非内容单元,类似于在非流利变体的书面和口语中观察到的"电报"风格.
- 开发的程序提供了一种节省时间的工具来评估和跟踪书面语言,这对于理解PPA中的语言和认知功能至关重要.
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