西班牙胰腺癌死亡率的趋势已经开始放缓了吗?
Lucía Cayuela1, Aurelio Cayuela Domínguez2
1Internal Medicine, Hospital Universitario Severo Ochoa, España.
Revista espanola de enfermedades digestivas
|August 4, 2023
概括
从1980年到2021年,胰腺癌死亡率在西班牙增加,但在某些地区和性别中,上升趋势已经放缓或稳定,特别是在纳瓦拉的30-64岁男性中.
科学领域:
- 流行病学 流行病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,胰腺癌仍然是癌症死亡的重要原因.
- 了解区域和性别特定的死亡率趋势对于有针对性的公共卫生干预至关重要.
研究的目的:
- 分析1980年至2021年间西班牙自治区 (ACs) 和性别的胰腺癌死亡率趋势.
主要方法:
- 一项生态趋势研究,利用国家统计局的综合数据.
- 根据年龄标准化的死亡率 (ASMR) 使用欧洲标准人口计算.
- 加入点回归分析确定了趋势,年度百分比变化 (APC) 和平均年度百分比变化 (AAPC).
主要成果:
- 从1980年到2021年,胰腺癌的总体ASMR在男性 (AAPC:1.5%) 和女性 (AAPC:1.8%) 中显著增加.
- 20世纪80年代末出现了转折点,最初的急剧增长随后趋势放缓.
- 虽然大多数AC显示ASMR的增加,但纳瓦拉在男性中呈现稳定率,在马德里和加利西亚注意到了表明趋势变化的特定拐点.
结论:
- 在西班牙,胰腺癌死亡率呈现上升趋势,在某些AC和性别中显著放缓或稳定.
- 这些发现表明死亡率趋势存在区域差异,突出显示了对本地化策略的需求.
- 进一步研究推动这些趋势的因素是有必要的.
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