尼古丁含量和喜欢口味对电子烟主观反应的影响:随机,安慰剂控制实验室研究
Michael P Bremmer1,2, Alana M Campbell3, Kai Xia3
1Department of Psychology & Neuroscience, Chapel Hill, NC, USA.
概括
电子液体的风味增强了vaping的满意度和味道,而尼古丁增加了奖励和渴望缓解. 这些影响是独立的,在常规的电子烟使用者中没有相互作用.
科学领域:
- 烟草监管科学 烟草监管科学
- 行为神经科学 行为神经科学
- 成研究研究成研究
背景情况:
- 电子液体的风味和尼古丁度影响电子烟的使用启动和维护.
- 尼古丁含量会影响成和戒烟的有效性.
- 关于香味和尼古丁对用户体验的联合影响的研究有限.
研究的目的:
- 调查电子液体风味和尼古丁对电子烟主观反应的独立和互动影响.
- 评估味道和尼古丁如何影响满足,奖励,厌恶,呼吸道感觉和渴望缓解.
主要方法:
- 89名经常使用电子烟的人参加了一项多次会议的研究.
- 参与者使用有偏好的风味 (果,薄荷,烟草) 或没有风味的电子液体,含有或不含有18毫克尼古丁.
- 使用节奏式vaping程序评估了主观影响.
主要成果:
- 尼古丁显著增加了心理奖励和渴望的缓解.
- 香味显著增强了vaping的满意度和味道.
- 尼古丁依赖的严重程度调节了尼古丁对奖励的影响.
结论:
- 电子液体的风味和尼古丁含量对主观的vaping反应有独立的,非互动的影响.
- 喜欢的味道增加了满意度和味道,但不会与尼古丁相互作用,改变奖励或渴望.
- 调查结果为电子尼古丁输送系统 (ENDS) 的监管政策提供了信息.
更多相关视频
08:39Generation of Electronic Cigarette Aerosol by a Third-Generation Machine-Vaping Device: Application to Toxicological Studies
Published on: August 25, 2018
25.6K
09:30A Microcontroller Operated Device for the Generation of Liquid Extracts from Conventional Cigarette Smoke and Electronic Cigarette Aerosol
Published on: January 18, 2018
8.4K
相关概念视频
Stimulants
245
Stimulants are substances that enhance neural activity and elevate dopamine levels in the brain, leading to their highly addictive nature. These drugs include cocaine, amphetamines, MDMA, caffeine, and nicotine, each with distinct mechanisms of action and varied health implications.
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...
245
Drugs Acting on Autonomic Ganglia: Stimulants
1.4K
Ganglionic stimulants activate NM nicotinic receptors in autonomic ganglia, falling into two categories: nicotine mimetics [e.g., lobeline, dimethylpiperazine, tetramethylammonium] and muscarinic receptor agonists [e.g., muscarine, methacholine]. The first category's action is rapid and blocked by nicotinic receptor antagonists, while the second category's action is delayed and blocked by atropine-like agents. Nicotine, an alkaloid, affects the heart rate by stimulating...
1.4K
