相关实验视频

Updated: Jul 20, 2025

Preterm EEG: A Multimodal Neurophysiological Protocol

Preterm EEG: A Multimodal Neurophysiological Protocol

Published on: February 18, 2012

过早分娩改变了大脑结构网络中节点聚类和神经连接模式的发展,在相当于月龄的年龄

Weihao Zheng¹, Xiaomin Wang¹, Tingting Liu²

¹Gansu Provincial Key Laboratory of Wearable Computing, School of Information Science and Engineering, Lanzhou University, Lanzhou, China.

Human brain mapping

|August 4, 2023

概括

过早出生会扰乱大脑网络的发展,改变大脑区域的局部连接,以相当于年龄的年龄. 这种局部网络漏洞,而不是全球拓,可能解释了早产婴儿的神经发育障碍.

科学领域:

神经科学是一个神经科学.
发育神经科学的发展神经科学.
脑部成像脑部成像

背景情况:

过早出生的新生儿经常经历神经发育障碍.
整个大脑的结构连接被破坏是一个潜在的原因.
了解纵向大脑网络的发展至关重要.

研究的目的:

研究从早产到代孕年龄 (TEA) 的纵向结构网络发展.
确定早产如何影响网络拓和局部大脑区域属性.
确定网络变化是否可以预测神经发育结果.

主要方法:

使用了来自开发人类结合体项目 (dHCP) 的多扩散权重MRI.
扫描了28名早产 (PB) 和28名晚产 (TB) 新生儿.
使用受约束的球形解卷曲曲谱 (constrained spherical deconvolution tractography) 构建结构性脑网络.

主要成果:

结构网络的发展显示,从早产到TEA的路径长度,聚类和模块化程度下降.
在TEA时,早产改变了特定大脑系统中的节点特性 (集群,模块内程度,参与系数).
局部网络属性以96.43%的准确度区分了早产和满产新生儿.

结论:

在产前期,结构网络的拓重组发生,从而优化了整体效率.
局部网络拓比全球网络组织更容易受到过早的攻击.
在早产婴儿中,局部网络属性的改变可能是认知和行为障碍的基础.

关键词:

这是分类分类的分类.图形理论中的图形理论.预产期前的时间.结构性网络网络的结构性网络术语相当的年龄是年龄.

更多相关视频

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

A Method for Investigating Age-related Differences in the Functional Connectivity of Cognitive Control Networks Associated with Dimensional Change Card Sort Performance

Published on: May 7, 2014

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats

Published on: November 20, 2015

相关概念视频

Neurulation

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the...