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Updated: Jul 20, 2025

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塔兹对MIR-224进行上调,以抑制多发性骨髓瘤中氧化应激反应

Samuel O Abegunde1,2, Stacy Grieve3, Tony Reiman1,2,4

  • 1Department of Biology, University of New Brunswick, Saint John, New Brunswick, Canada.

Cancer reports (Hoboken, N.J.)
|August 4, 2023
PubMed
概括

瘤抑制剂TAZ通过诱导miR-224来促进多发性骨髓瘤 (MM) 细胞对氧化应激的敏感性,从而抑制NRF2抗氧化剂程序. 这一途径为MM治疗提供了一个新的目标.

关键词:
这就是NRF2的NRF2.塔兹 (TAZ) 是一个名为塔兹 (TAZ) 的城市.在 miR-2244 系统中,它是 miR-2244.多发性骨髓瘤是多发性骨髓瘤的一种.氧化应激是一种氧化应激.

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