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相关概念视频

Glaucoma: Overview01:25

Glaucoma: Overview

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Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Angle Closure Glaucoma: Treatment01:28

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Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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相关实验视频

Updated: Jul 20, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
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时间光盘微血管在眼中脱落.

Yeon Ju Lim1, Jong Wook Bang1, Robert N Weinreb2

  • 1Department of Ophthalmology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, South Korea.

Investigative ophthalmology & visual science
|August 4, 2023
PubMed
概括

在初级开角青光眼中,焦点时微血管的脱落与较长的轴长度和光盘变化有关. 这表明轴延长可能导致光盘微血管缺失.

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Evaluation of Capillary and Other Vessel Contribution to Macular Perfusion Density Measured with Optical Coherence Tomography Angiography
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相关实验视频

Last Updated: Jul 20, 2025

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科学领域:

  • 眼科医生 眼科 眼科
  • 玻璃眼研究研究 玻璃眼研究
  • 光学连贯性断层扫描血管学

背景情况:

  • 主要开角青光眼 (POAG) 是不可逆转失明的主要原因.
  • 光盘中的微血管流失 (MvD-D) 是绿眼病进展的早期迹象.
  • 了解MvD-D的模式,特别是在部区域,对于诊断和管理至关重要.

研究的目的:

  • 为了研究焦点时光光盘微血管性脱落 (MvD-D) 的临床特征,在患有初级开角玻璃眼 (POAG) 的患者中.
  • 区分隔离焦点时MvD-D和其他时MvD-D的模式.

主要方法:

  • 在Swept-Source光连贯断层扫描血管学 (SS-OCTA) 上分析了POAG患者MvD-D的187只眼睛.
  • 根据时间性MvD-D模式,患者被分为三个组:焦点 (组1),超级/下限时 (组2) 和扩散时 (组3).
  • 临床特征包括轴距长度,膜缩,光盘形态和视网膜神经纤维层 (RNFL) 厚度在各组之间进行了比较.

主要成果:

  • 第1组 (焦点时MvD-D) 与其他组相比,显示了显著更长的轴长,更大的β-区域偏性缩,更大的水平倾斜和卵性指数.
  • 与第二组相比,第一组的时间RNFL也较薄,尽管其他部门的厚度相似.
  • 与第1组和第2组相比,3组 (扩散时间MvD-D) 在大多数领域显示出明显较差的视野平均偏差和较薄的RNFL.

结论:

  • 在POAG中,焦点时MvD-D与轴长度增加和随后的光盘形态变化有关.
  • 轴延长似乎是导致时间光盘微血管缺失的重要因素.
  • 这些发现凸显了SS-OCTA在识别特定的MvD-D模式及其与青光眼严重程度和潜在结构变化的相关性方面的重要性.