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Updated: Jul 20, 2025

An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes
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An Oligonucleotide-based Tandem RNA Isolation Procedure to Recover Eukaryotic mRNA-Protein Complexes

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通过无细胞转录翻译平台识别反意义寡核酸来破坏小RNA调节的抗生素耐药性

Min Jen Tsai1, Raphael Angelo I Zambrano1,2, Jeremiah Lyn Susas1

  • 1Department of Biology, California State University Northridge, Northridge, California 91330, United States.

ACS synthetic biology
|August 4, 2023
PubMed
概括

这项研究引入了一种无细胞试验,以设计有效的抗意义寡核酸 (ASO),向细菌小RNA (sRNA). 这些核酸 (PNA) ASO通过向MicFsRNA显示了减少抗生素耐药性的协同效应.

关键词:
抗生素耐药性 抗生素耐药性这是一种反感性寡核酸 (ASO).无细胞转录-翻译 (TX-TL)调节sRNA的调节

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