在单肢膝关节骨关节炎患者的下腿骨矿物质密度的比较
Yun Seong Choi1, Jin-Uk Jeong1, Seung Hoon Lee2
1Department of Orthopedic Surgery, Veterans Health Service Medical Center, 53 Jinhwangdo-ro 61-gil, Gangdong-gu, Seoul, 05368, South Korea.
Archives of orthopaedic and trauma surgery
|August 4, 2023
概括
膝关节骨关节炎 (OA) 与受影响侧的股骨部的较低骨矿物质密度 (BMD) 有关. 肢体对齐差异不会影响这种BMD减少,这表明OA本身会降低骨密度.
科学领域:
- 整形外科 整形外科 整形外科
- 类风湿病学 类风湿病学
- 骨的新陈代谢 骨的新陈代谢
背景情况:
- 膝关节骨关节炎 (OA),骨矿物质密度 (BMD) 和下肢对齐之间的相互作用仍然不完全理解.
- 研究这些关系对于理解OA病理生理学和治疗至关重要.
研究的目的:
- 为了检查膝关节OA,逆侧四肢BMD和对齐之间的关系.
- 为了确定对齐差异是否会影响单侧膝关节OA的患者的骨硬化.
主要方法:
- 对149名接受单肢全膝关节整形手术 (TKA) 的患者的回顾性分析.
- 纳入标准:Kellgren-Lawrence (KL) 在经营方面具有III-IV等级,在抵押方面具有KL等级I-II等级.
- 排除标准:创伤性OA,以前影响下肢对齐的手术和骨折. 在四肢和患者组之间比较了近端大腿骨骨质量和对齐差异.
主要成果:
- 与非OA侧相比,OA侧的腿部部BMDT分数显著较低 (p < 0.001).
- 没有发现BMD和四肢对齐之间有显著的相关性.
- 在对齐差异>5°和<5°的组之间,骨质量没有差异.
结论:
- 单侧膝关节OA与受影响侧的股骨部 BMD 减少有关.
- 在这种情况下,四肢对齐差异似乎不会影响BMD.
- 观察到的BMD减少主要归因于膝关节OA,而不是肢体对齐的改变.
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