在TaTME手术后的口腔逆转后,Clostridium difficile感染的预测因素
Flavio Tirelli1, Laura Lorenzon2, Alberto Biondi1
1General Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Largo Francesco Vito 1, 00168, Rome, Italy.
Updates in surgery
|August 4, 2023
概括
在经过门的全腹腔切除手术 (TaTME) 后延迟的静脉管逆转会增加患上困难菌感染 (CDI) 的风险. 迅速逆转是预防这种术后并发症的关键.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 传染性疾病 传染性疾病
背景情况:
- 过门全腹腔切除术 (TaTME) 是用于直肠癌的手术技术.
- 胃口逆转是TaTME后的一个常见的后续程序.
- 困难菌感染 (CDI) 是一个潜在的术后并发症.
研究的目的:
- 为了确定在TaTME患者的口腔逆转后CDI的发病率.
- 为了确定与术后CDI相关的变量.
主要方法:
- 在TaTME (2015-2023) 后,对126名经历了口腔静脉逆转的患者进行了回顾性审查.
- 根据手术后腹的严重程度和CDI状态分类成组.
- 对CDI预测器的临床/实验室数据和机器学习的分析.
主要成果:
- 观察到住院CDI的发病率为4.8% (6/126名患者).
- 延迟的静脉管逆转 (平均68.4周与44.6周) 与CDI有显著的相关性.
- 机器学习发现延迟关闭是腹预测因素;男性和接受新辅助/辅助疗法的人患腹的概率更高.
结论:
- 在TaTME之后的口腔逆转手术与中度的住院CDI率有关.
- 静脉口腔逆转的时间间隔是影响CDI风险的关键因素.
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