心脏外科手术后的前24小时内荷尔蒙变化
Balázs Szécsi1, Krisztina Tóth1, András Szabó2
11Doctoral School of Theoretical and Translational Medicine, Semmelweis University, Budapest, Hungary.
Physiology international
|August 4, 2023
概括
在心脏手术后,甲状腺激素 (T3) 和丸激素水平显著下降. 益生素 (PRL) 和甲状腺素 (T4) 水平保持稳定. 这些荷尔蒙变化可能表明疾病的严重程度和心脏手术后的恢复.
科学领域:
- 内分泌学 在内分泌学.
- 心血管外科心血管外科
- 临界护理医学 临界护理医学
背景情况:
- 由于神经激素反,心脏手术后荷尔蒙波动很常见.
- 这些变化可能会影响患者的结果,包括发病率和死亡率.
研究的目的:
- 分析心脏手术后24小时内甲状腺和性激素的变化.
- 研究激素水平与临床结果之间的关系.
主要方法:
- 对49名接受心脏手术的患者进行前性观察性研究.
- 在手术前和手术后24小时内测量甲状腺激素 (TSH,T3,T4) 和性激素 (益生菌,).
主要成果:
- 观察到T3和总水平的显著下降 (P < 0.001).
- TSH水平也显著下降 (P<0.001),而T4和益生菌素没有显著变化.
- 手术后的荷尔蒙水平与ICU停留,机械呼吸和MELD分数相关.
结论:
- 降低T3可能表明非甲状腺疾病综合征.
- 水平可能反映肝功能障碍.
- 孕激素可以作为女性患者的压力激素标记物.
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