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1-Oleoyl-lysophosphatidylethanolamine刺激了TH17细胞中的RORγt活动

Yusuke Endo1,2,3, Toshio Kanno1, Takahiro Nakajima1

  • 1Department of Frontier Research and Development, Laboratory of Medical Omics Research, Kazusa DNA Research Institute, 2-6-7 Kazusa Kamatari, Kisarazu, Chiba 292-0818, Japan.

Science immunology
|August 4, 2023
PubMed
概括

1-oleoyl-lysophosphatidylethanolamine通过调节RORγt活性来促进T助手17 (TH17) 细胞的分化. 这种脂质代谢物对介素-17 (IL-17) 生产和TH17细胞的致病性至关重要,影响自身免疫性疾病模型.

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