针对B细胞治疗系统性硬化症
Hitoshi Terui1, Yuichiro Segawa, Yoshihide Asano
1Department of Dermatology, Tohoku University Graduate School of Medicine, Japan.
Current opinion in rheumatology
|August 4, 2023
概括
功能障碍的B细胞与系统性硬化症 (SSc) 的病原发生有关. 针对B细胞的疗法对治疗SSc有前途,目前正在进行试验,探索CD20和BAFF等点.
科学领域:
- 免疫学 免疫学 免疫学
- 类风湿病学 类风湿病学
- 细胞生物学 细胞生物学
背景情况:
- 系统性硬化症 (SSc) 的发病因子越来越多地与B细胞功能障碍有关.
- 了解B细胞参与对于开发有效的SSc治疗至关重要.
结论:
- 针对B细胞的向疗法具有很大的潜力,可以解决SSc.的未满足需求.
- 需要进一步的大规模临床研究来验证这些方法.
- B细胞代表了改善SSc症状的有希望的治疗途径.
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