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Updated: Jul 20, 2025

An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry
11:09

An HS-MRM Assay for the Quantification of Host-cell Proteins in Protein Biopharmaceuticals by Liquid Chromatography Ion Mobility QTOF Mass Spectrometry

Published on: April 17, 2018

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开发一种潜在的初级方法,通过电子喷雾差分流动性分析量化蛋白质.

Wei Mi1, Xinyi Zhang1, Xiangrong Tian2

  • 1National Institute of Metrology, No.18 Beisanhuan Donglu, Beijing, 100029, China.

Talanta
|August 4, 2023
PubMed
概括

一种使用电喷差分流动性分析与凝结粒子计数器 (ES-DMA-CPC) 的新蛋白质量化方法提供了准确的测量结果. 这种ES-DMA-CPC方法显示出作为一种主要量化技术的前景,它补充了现有的同位素稀释质谱法 (IDMS) 方法.

关键词:
电子喷雾差分移动性分析-冷凝颗粒计数器 (ES-DMA-CPC) 的应用.同位素稀释质谱法 (IDMS) 是一种质谱法.潜在的初级方法.蛋白质量化量化的蛋白质.紫外线-VIS光谱光度计

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