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Updated: Jul 20, 2025

Efficient Purification and LC-MS/MS-based Assay Development for Ten-Eleven Translocation-2 5-Methylcytosine Dioxygenase
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Published on: October 15, 2018

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通过TET2介导的mRNA去甲基化调节白血病干细胞的定位和自我更新

Yangchan Li1, Meilin Xue2, Xiaolan Deng3

  • 1Department of Systems Biology, Beckman Research Institute of City of Hope, Monrovia, CA 91016, USA; Department of Radiation Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, Guangdong, China.

Cell stem cell
|August 4, 2023
PubMed
概括

甲基细胞二氧化酶2 (TET2) 缺乏促进急性髓性白血病 (AML) 通过增强白血病干细胞 (LSC) 回归骨髓利基. 这通过TET2驱动的Tetraspanin 13 (TSPAN13) 表达的增加而发生.

关键词:
在CXCR4中,CXCR4是最常见的.甲基化RNA5-甲基细胞因子甲基化在TET2的基础上.在TSPAN13中使用.YBX1 一个字母.骨髓微环境 骨髓微环境在家里找回来.白血病的干细胞是什么?移民 移民 迁移 迁移它是自我更新的.

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