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猛龙的O-GlcNAcylation将葡萄糖信号转化为mTORC1的信号

Chenchen Xu1, Xiaoqing Pan2, Dong Wang1

  • 1State Key Laboratory of Membrane Biology, New Cornerstone Science Laboratory, Institute of Molecular Medicine, College of Future Technology, Peking University, Beijing 100871, China.

Molecular cell
|August 4, 2023
PubMed
概括

葡萄糖水平通过O-GlcNAcylation of Raptor控制细胞生长,这是一个关键的mTORC1蛋白. 这一过程通过促进mTORC1向 lysosome的移动来增强mTORC1的激活,而AMPK信号抑制mTORC1.

关键词:
这是一种O-GlcNAcylation.猛禽猛禽是一种猛禽.感应葡萄糖的感应.在mTOROR中使用.

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