发展原发性乳腺癌和原发性卵巢癌的危险因素:系统性审查
Jennifer S Ferris1, Devon A Morgan1, Ashley S Tseng1
1Department of Epidemiology, Mailman School of Public Health, Columbia University, 722 W 168th St, New York, NY 10032, USA.
Critical reviews in oncology/hematology
|August 4, 2023
概括
患有乳腺癌 (BR) 的女性有较高的卵巢癌 (OV) 风险,反之亦然. 本综述确定了影响这些风险的瘤特征,遗传和家族因素,帮助临床决策.
科学领域:
- 在瘤学瘤学.
- 癌症流行病学 癌症流行病学
- 遗传学 是一个遗传学.
背景情况:
- 被诊断为乳腺癌 (BR) 的女性面临患初级卵巢癌 (OV→BR) 的风险较高.
- 相反,患有卵巢癌 (OV) 的女性患初级乳腺癌 (BR→OV) 的可能性增加.
- 了解共同和独特的风险因素对于管理这些双重癌症风险至关重要.
结论:
- 瘤特征,遗传倾向 (例如,BRCA突变) 和家族癌症史显著影响发展二次乳腺或卵巢癌的风险.
- 这些发现可以为被诊断为乳腺癌或卵巢癌的患者提供临床决策信息.
- 确定特定的风险因素可能有助于针对高风险个体实施有针对性的降低风险的策略.
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