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Updated: Jul 20, 2025

Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy
09:37

Optimized Negative Staining: a High-throughput Protocol for Examining Small and Asymmetric Protein Structure by Electron Microscopy

Published on: August 15, 2014

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揭示了表面脂质对高密度脂蛋白的结构,动态和相互作用的影响

Chris J Malajczuk1, Ricardo L Mancera1

  • 1Curtin Medical School, Curtin Health Innovation Research Institute and Curtin Institute for Data Science, Curtin University, GPO Box U1987, Perth, WA 6845, Australia.

Biochimica et biophysica acta. Biomembranes
|August 4, 2023
PubMed
概括

表面脂质,如基米林 (SM) 影响高密度脂蛋白 (HDL) 的结构和动态. 将SM添加到HDL模型中可以提高阿波利波蛋白AI的灵活性,并改变脂质相互作用,从而影响HDL.

关键词:
在阿波利波蛋白A-I.高密度脂蛋白是一种高密度脂蛋白.低丰富度的脂质是一种低丰富度的脂质.分子动力学模拟模型斯芬戈脂类是指状的脂类.

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Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles09:15

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