SETDB1 MCT1 穿

Xiaowei She1, Qi Wu1, Zejun Rao1

  • 1GI Cancer Research Institute, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, 430030, P. R. China.

概括

通过K473三甲基化,SET域分叉1 (SETDB1) 通过K473三甲基化稳定单碳酸盐载体1 (MCT1). 这种修改通过促进糖解和巨细胞两极分化来增强结直肠癌的进展,这表明MCT1甲基化作为治疗点.

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