患有风湿和肌肉骨疾病的患者的疲劳:对定义,测量仪器,决定因素,后果和干预措施的范围审查
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Esther Beckers1,2, Kasper Hermans1,2, Astrid Van Tubergen1,2
1Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands.
RMD open
|August 4, 2023
概括
类风湿性关节炎和其他疾病中的疲劳缺乏明确的定义和有效的治疗方法. 患者的意见强调了针对性管理计划和进一步研究的需要.
科学领域:
- 类风湿病学 类风湿病学
- 临床实践 临床实践
- 系统审查是系统的审查.
背景情况:
- 疲劳是类风湿性关节炎 (RA),脊椎关节炎,骨关节炎和纤维肌痛的复杂和普遍症状.
- 现有的文献评论提供了关于疲劳的定义,测量,决定因素,后果和干预有效性的见解.
- 了解这些方面对于改善临床管理和患者结果至关重要.
研究的目的:
- 系统地审查有关RA疲劳,脊椎关节炎,骨关节炎和纤维肌痛的出版文献.
- 综合关于疲劳定义,测量,决定因素,后果和临床实践相关的干预有效性的证据.
- 纳入患者的观点,为研究和临床建议提供信息.
主要方法:
- 在五个数据库中对评论进行系统的文献搜索.
- 基于评论类型 (科克兰,系统,叙事) 和出版年份的层次数据提取.
- 提取数据的叙述综合,结果由患者小组讨论.
主要成果:
- 包括134项审查;没有发现对一般或特定类型的疲劳达成一致的定义.
- 确定了25个自我报告的测量仪器,其中五个建议过度疲劳的门值.
- 疼痛,身体功能,抑郁症状,女性性别和压力是关键决定因素;工作表现和社会角色是显著的后果. 干预的影响范围从微不足道到中度.
结论:
- 风湿性疾病中的疲劳是复杂的,缺乏标准化的定义和测量工具.
- 有证据表明,疲劳与其决定因素/后果之间存在很小的关联.
- 综合的证据可以指导量身定制的管理计划和未来的研究重点.
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