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AT-hook 是 SWI/SNF 的一个进化保守的自我调节域,它是细胞谱系原始化所需的

Dhurjhoti Saha1,2, Solomon Hailu1,2,3, Arjan Hada1,2

  • 1Department of Epigenetics and Molecular Carcinogenesis, Univ. of Texas MD Anderson Cancer Center, Houston, TX, 77230, USA.

Nature communications
|August 4, 2023
PubMed
概括

在SWI/SNF染色体重塑剂中的AT-hook基因调节DNA结合和ATPase活性. 这种调节对基因转录,细胞分化和酵母和小鼠模型中的细胞生长至关重要.

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