来自两个亚洲流行HIV-1CRF的Envtrimers的结构和免疫识别

Jun Niu1,2,3, Qi Wang1, Wenwen Zhao1

  • 1Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai, 201210, China.

Nature communications
|August 4, 2023
PubMed
概括

我们从流行的循环复合形式 (CRF) 确定了HIV-1 Envs的冷-EM结构. 这些结构揭示了独特的特征和抗体的新型中和机制,有助于免疫聚焦疫苗设计.

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