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Updated: Jul 20, 2025

Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice
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Induction of Intestinal Inflammation by Adoptive Transfer of CBir1 TCR Transgenic CD4+ T Cells to Immunodeficient Mice

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降低TMIGD1会通过克罗恩病的BANF1-NF-κB通路加剧结肠炎和肠壁功能障碍

Longyuan Zhou1, Liguo Zhu1, Xiaomin Wu1

  • 1Department of Gastroenterology, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, Guangdong, People's Republic of China.

BMC medicine
|August 4, 2023
PubMed
概括

含有跨膜和免疫球蛋白域蛋白1 (TMIGD1) 维护肠道屏障的完整性,并减少克罗恩病 (CD) 中的炎症. TMIGD1是CD的潜在治疗标,因为它的表达预测了治疗反应.

关键词:
在 BANF1 中使用.克罗恩氏病是什么 克罗恩氏病是什么肠道上皮质屏障 肠道上皮质屏障通过NF-κB路径.在TMIGD1中使用TMIGD1.

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