在患有副鼻的患者中进行食道高分辨率计量技术成功
Daniel L Cohen1, Anton Bermont2, Vered Richter2,3
1The Gonczarowski Family Institute of Gastroenterology and Liver Diseases, Shamir (Assaf Harofeh) Medical Center, 70300, Zerifin, Israel. docdannycohen@yahoo.com.
Dysphagia
|August 5, 2023
概括
高分辨率测量仪 (HRM) 在患有性分歧器 (ED) 的患者中通常是不成功的,原因是难以穿过食管胃结. 对于这些患者,可能需要使用替代诊断方法.
科学领域:
- 胃肠病学和消化系统健康
- 诊断成像和程序的诊断成像和程序
- 食道和吞障碍 饮食管和吞障碍
背景情况:
- 高分辨率计量 (HRM) 是诊断食道运动障碍的标准,但存在技术上的挑战.
- 位于远隔食道的腹分泌管 (ED) 经常与潜在的食道运动问题有关.
- 之前的研究强调了HRM的诊断效用,但其在特定患者群体中的成功率需要进一步调查.
研究的目的:
- 评估HRM在患有发性分泌管 (ED) 的患者的技术成功率.
- 为了比较ED患者,阿喀拉西亚患者和健康对照人群之间的HRM成功率.
- 确定影响ED患者HRM成功或失败的因素.
主要方法:
- 对2008年至2022年期间在单一中心进行的HRM研究进行了回顾性分析.
- 20名ED患者与76名阿喀拉西亚患者和199名对照患者的比较,不包括儿科病例,先前的治疗和镇静/内镜辅助.
- 完全成功被定义为≥7个可解释的吞,通过整个食道到胃的测量.
主要成果:
- 在70.0%的ED患者中,HRM取得了完全成功,而在阿喀拉西亚患者中为85.5%,在对照组中为91.0%.
- 无法穿过食管胃结 (EGJ) 是ED和阿卡拉西亚组中失败的主要原因.
- 更大的分歧体大小与更低的HRM技术成功有显著的关联 (40%对小分歧体100%,p=0.013).
结论:
- 膜分歧管 (ED) 是高分辨率测量仪 (HRM) 失败的重要预测因素.
- 在ED患者中,HRM失败的主要原因似乎是无法穿过食管胃结口,通常是由于分泌器的大小.
- 对于患有ED的患者,应考虑使用内镜辅助HRM等替代诊断方法,因为传统HRM的失败概率很高.
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