描述和定义与神经刺激相关的睡眠呼吸障碍
Ashley L Garrett1, Jason Burch2, Yue Zhang3
1Pulmonary Division, Mayo Clinic, Scottsdale, AZ, USA.
Sleep medicine
|August 5, 2023
概括
阴道神经刺激器 (VNS) 的使用导致睡眠呼吸障碍 (SDB),标准标准无法检测到. 其他评分方法更好地捕捉这些干扰,但正气道压力治疗是无效的.
科学领域:
- 睡眠医学 睡眠医学
- 神经学 神经学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 阴道神经刺激剂 (VNS) 用于和抑郁症.
- VNS可以引起独特的睡眠呼吸障碍 (SDB) 事件.
- 标准标准可能无法准确检测SDBVNS.
研究的目的:
- 将美国睡眠医学学会 (AASM) 的标准标准与 SDBVNS检测的新标准进行比较.
- 评估SDBVNS和对正气道压力 (PAP) 治疗的反应的临床相关性.
主要方法:
- 对接受多睡眠图的VNS成年患者的回顾性分析.
- 将AHIAASM与三个特定于VNS的下垂症标准进行比较 (AHIVNS0,AHIVNS2,AHIVNS3).
主要成果:
- 新的标准确定了SDBVNS在明显更多的患者比AHIAASM.
- VNS事件与增加的兴奋或低氧化症无关.
- PAP治疗没有显示SDBVNS的改善.
结论:
- 标准的AASM标准低估了VNS引起的呼吸障碍.
- SDBVNS可能缺乏临床意义的低氧化和唤醒.
- 对于与VNS相关的睡眠呼吸障碍,PAP治疗是无效的.
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