之前感染 Bordetella bronchiseptica 增强了殖民,但并没有感染 Streptococcus suis 的疾病
Samantha J Hau1, Daniel W Nielsen2, Susan L Brockmeier1
1National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA, United States.
Veterinary microbiology
|August 5, 2023
概括
Bordetella bronchiseptica的殖民化并没有增加猪中Streptococcus suis的疾病. 然而,共感染增强了S. suis的鼻腔殖民,这表明在压力或免疫受损的猪中疾病增加的可能性.
科学领域:
- 兽医微生物学 兽医微生物学
- 猪病理学 猪病理学
- 传染性疾病 传染性疾病
背景情况:
- 甲状病毒和Streptococcus suis是重要的猪病原体.
- B. bronchiseptica会导致呼吸系统疾病,并可能增加对其他病原体的敏感性.
- S. suis 导致猪呼吸道疾病复合体,并导致全身感染.
研究的目的:
- 研究B. bronchiseptica殖民对S. suis殖民,传播和疾病的影响.
- 为了比较这些效应在传统和剖腹产衍生,缺乳母乳 (CDCD) 猪仔.
主要方法:
- 猪被挑战了单独的S. suis,单独的B. bronchiseptica,或者B. bronchiseptica之后的S. suis.
- 进行了两项研究:一项是使用常规猪,一项是使用CDCD猪.
主要成果:
- 在这两项研究中,用B. bronchiseptica进行预注射并没有增加S. suis疾病的发病率.
- 与仅感染S. suis的猪相比,同感染的猪中S. suis的鼻腔殖民性更高.
- B. bronchiseptica的殖民水平在单一和共感染的动物之间是相似的.
结论:
- 仅靠B. bronchiseptica的殖民并不能使猪中S. suis引起的疾病恶化.
- 与B. bronchiseptica的同时感染可以增强S. suis的鼻腔殖民.
- 这种增强的殖民可能会增加在压力或免疫受损条件下疾病的风险.
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