相关实验视频
Updated: Jul 20, 2025

07:22
Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
8.3K
皮肤测试指导的策略,在患有立即过敏反应的患者中选择替代性含的对比介质:一项前性确认性研究
Ji-Hyang Lee1, Youngsang Yoo2, Sung-Ryeol Kim3
1Department of Allergy and Clinical Immunology, Asian Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
The journal of allergy and clinical immunology. In practice
|August 5, 2023
概括
以皮内皮肤测试 (IDT) 为指导的策略有效地预防了对含对比剂 (ICM) 的立即过敏反应 (IHR). 这种方法可以减少ICM反应的病史患者的IHR复发和严重程度.
科学领域:
- 过敏和免疫学 过敏和免疫学
- 放射学 放射学是一门学科.
- 药理学 药理学是指药理学的学科.
背景情况:
- 含的对比剂 (ICM) 经常会引起立即的过敏反应 (IHR).
- 在临床上,经常需要重复使用ICM,因此需要采取策略来预防复发的过敏症.
- 需要标准化的协议来管理患者有史以来的IHR到ICM.
研究的目的:
- 建议和评估一种以皮内皮肤测试 (IDT) 为指导的策略,以防止以前暴露于ICM的患者的IHR复发.
- 确定安全的替代ICM药物,用于皮肤测试结果为罪祸首ICM的患者.
主要方法:
- 一项前性多中心研究涉及有IHR至ICM病史的患者.
- 用致病性ICM进行皮内皮肤测试 (IDT). 根据IDT结果选择了替代ICM.
- 患者接受了随后的计算机断层扫描检查与前期治疗,并评估过敏的复发/严重性.
主要成果:
- 在496名注册参与者中,有299人再次接触ICM.
- 269名参与者遵循了IDT指导的协议,其中84.8%没有出现任何不良反应.
- 相比之下,没有遵循协议的53.3%的参与者经历了复发的IHR (P < .001).
- 该协议还显著降低了IHR的严重程度,在发生反应的情况下 (P = 0.003).
结论:
- 一个IDT指导的策略是有效的减少IHR的复发ICM.
- 这种方法还可以减轻患有复发的患者过敏反应的严重程度.
- 这项研究支持IDT对诊断ICM过敏和确定安全替代品的建议.
相关概念视频
Radiological Investigation I: X-ray and CT
289
Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and...
289
Imaging Studies III: Computed Tomography
28
DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
28
Imaging Studies for Cardiovascular System V: CT
42
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
42
Imaging Studies I: CT and MRI
280
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
280
Hypersensitivities
739
Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...
739
Allergic Drug Reactions
876
Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing...
876

