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Updated: Jul 20, 2025

Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis
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Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis

Published on: July 16, 2021

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系统性炎症和随后的肌缩性侧面硬化症风险:前性队列研究

G David Batty1, Mika Kivimäki2, Philipp Frank1

  • 1Department of Epidemiology and Public Health, University College London, UK.

Brain, behavior, and immunity
|August 5, 2023
PubMed
概括

由C-反应蛋白 (CRP) 表示的全身炎症与患有肌缩性侧面硬化症 (ALS) 的风险更高有关. 这项研究发现,较高的CRP水平预测ALS死亡率和住院病例的增加.

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Primary Cultures of Rat Astrocytes and Microglia and Their Use in the Study of Amyotrophic Lateral Sclerosis

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Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets11:03

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相关概念视频

Amyloid Fibrils03:03

Amyloid Fibrils

Amyloid fibrils are aggregates of misfolded proteins.  Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils. 
Amyloid deposits were observed as early as 1639 in the liver and the spleen.   In 1854, Rudolph Virchow performed iodine staining,...
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