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Updated: Jul 20, 2025

Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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Published on: November 15, 2013

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ncBAF增强了人类和小鼠肝脏中PXR介导的转录激活

Kiamu Kurosawa1, Masataka Nakano2, Itsuki Yokoseki1

  • 1Drug Metabolism and Toxicology, Faculty of Pharmaceutical Sciences, Kanazawa University, Kakuma-machi, Kanazawa 920-1192, Japan.

Biochemical pharmacology
|August 5, 2023
PubMed
概括

含有蛋白9 (BRD9) 的布罗姆多马因与Pregnane X受体 (PXR) 相互作用,增强其活性. 用iBRD9抑制BRD9可以减少PXR介导的不良药物反应,如药物相互作用和肝脏问题.

关键词:
含有蛋白质9的布罗姆多马因.染色体重塑 染色体重塑 的方法细胞染色体P450的使用.药物代谢药物代谢脱脂血症是什么意思 脱脂血症是什么意思孕妇的X受体受体.

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