牙科手术和周围假肢关节感染之间的关联:一个案例交叉研究
Soichiro Masuda1, Toshiki Fukasawa2, Masato Takeuchi3
1Department of Orthopaedic Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan; Department of Pharmacoepidemiology, Graduate School of Medicine and Public Health, Kyoto University, Kyoto, Japan.
概括
牙科手术不会增加晚期周围假肢关节感染 (LPJI) 的风险. 这一发现质疑在牙科手术前对患者进行抗生素预防的必要性.
科学领域:
- 整形外科 整形外科 整形外科
- 传染性疾病 传染性疾病
- 牙科医学 牙科医学
背景情况:
- 牙科手术可能导致细菌血症,但它们与晚期周围假肢关节感染 (LPJI) 的联系尚未得到充分证实.
- 关于牙科干预和LPJI风险之间的关联的证据有限.
研究的目的:
- 调查牙科手术是否与晚期周围假肢关节感染 (LPJI) 的风险增加有关.
主要方法:
- 一个案例交叉研究利用了2014年4月至2021年9月的日本索赔数据库.
- 对因LPJI住院的成年患者进行了分析,将入院前1-4周 (病例期) 的牙科手术暴露与前9-12周和17-20周 (控制期) 的牙科手术暴露进行了比较.
- 条件后勤回归计算了与牙科手术相关的LPJI的几率比率 (OR) 和95%置信区间 (CI).
主要成果:
- 这项研究包括241名LPJI患者.
- 在实验期间,19.1%的患者进行了牙科手术,在对照期间,31.1%的患者进行了牙科手术.
- 牙科手术后LPJI的几率比为0.96 (95% CI,0.61-1.53),表明没有显著的关联 (p=0.88).
结论:
- 牙科手术似乎与晚期周围假肢关节感染 (LPJI) 的风险增加无关.
- 这些发现可能会促使重新评估常规抗生素预防的建议,在牙科手术前,为患者的关节植入物.
相关概念视频
01:26Factors Affecting the Risk of Infection
11.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K
01:22Healthcare Associated Infections II: Preventive Measures
2.7K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.7K
01:15Teeth
487
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
487
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.3K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.3K
01:25Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
41
Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
41