在喘中对吸入性皮质类固醇和长效β2-激动剂的坚持:MASK-air研究
B Sousa-Pinto1,2, R Louis3,4, J M Anto5,6,7
1MEDCIDS - Department of Community Medicine, Information and Health Decision Sciences; Faculty of Medicine, University of Porto, Porto, Portugal.
Pulmonology
|August 5, 2023
概括
使用MASK-air应用程序的喘患者对吸入性皮质类固醇和长效β-激动剂 (ICS+LABA) 具有很高的坚持. 虽然ICS+formoterol (ICS+F) 用户的坚持度较低,但他们报告了较少的短效β-激动剂 (SABA) 使用和类似的喘控制.
科学领域:
- 数字健康数字健康
- 呼吸系统医学 呼吸系统医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 喘管理在评估和改善控制器药物坚持方面面临挑战.
- 移动健康 (mHealth) 应用程序为监控遵守提供了一个潜在的解决方案.
- 控制药物,特别是吸入性皮质类固醇 + 长效β2-激动剂 (ICS+LABA),对于控制喘至关重要.
研究的目的:
- 评估MASK-air®应用程序用户对ICS+LABA的遵守情况.
- 为了比较ICS+formoterol (ICS+F) 和ICS+其他LABA之间的粘附性.
- 为了研究ICS+LABA坚持和喘控制或短效β-激动剂 (SABA) 使用之间的关联.
主要方法:
- 分析了来自27个国家的2015-2022年的MASK-air®数据.
- 在ICS+F和ICS+其他LABA用户之间比较坚持,症状和症状治疗得分.
- 回归建模以评估坚持和喘控制/SABA使用之间的联系,并进行敏感性分析.
主要成果:
- 与ICS+F (59.3%) 相比,ICS+其他LABA (75.1%) 的坚持率更高 (每周使用≥80%).
- 两组人都表现出类似的喘控制和工作生产力.
- ICS+其他LABA使用者报告的SABA使用日数 (中位数为71.4%) 超过ICS+F使用者 (中位数为57.1%).
- 增加每周使用ICS+F或ICS+其他LABA与每周使用SABA的风险降低有关.
结论:
- 使用MASK-air应用程序的喘患者表现出对ICS+LABA的高度坚持.
- ICS+F使用者表现出较低的坚持,但也减少了SABA使用和可比的喘控制.
- 这些发现突显了mHealth应用程序在监测喘药物治疗的潜力.
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