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乳腺癌的放射治疗拒绝与乳腺保护手术

Jiameng Liu¹, Zhanlin Zhu¹, Zhipeng Hua¹

¹Department of Breast Surgery, Women and Children's Hospital, School of Medicine, Xiamen University, No.10, Zhenhai Road, Xiamen, 361003, Fujian Province, China.

Radiation oncology (London, England)

|August 5, 2023

概括

许多乳腺癌患者在经过乳腺保护手术后拒绝放射治疗,年龄较大和低收入等因素影响了这一决定. 了解这些风险因素对于改善治疗坚持和治疗结果至关重要.

科学领域:

在瘤学瘤学.
公共卫生公共卫生

背景情况:

在乳腺癌的乳腺保护手术后,放射治疗是标准的.
显著的比例的患者拒绝这种辅助治疗.
确定拒绝原因对于患者护理至关重要.

研究的目的:

为了调查放射治疗拒绝后乳房保护手术的趋势.
确定与拒绝放射治疗相关的人口和临床风险因素.

主要方法:

使用了监测,流行病学和最终结果 (SEER) 数据库 (2010-2015).
使用多变量Cox模型,比较放射治疗和拒绝组之间的生存率.
通过多变量逻辑回归分析了拒绝的影响因素,并开发了一个名ogram.

主要成果:

87,100名患者接受了乳腺保护手术; 2.5%的人拒绝放射治疗.
放射治疗拒绝率从2010年的2.1%增加到2015年的3.1%.
年龄较大,收入较低,离婚,白人,晚期和没有化疗都与拒绝有关.

结论:

手术后的放射治疗增强了乳房保护手术的好处.
某些患者群体,包括老年人,低收入人群,离婚者,白人和没有接受化疗的晚期患者,更有可能拒绝放射治疗.

关键词:

乳腺癌乳腺癌乳腺癌乳腺癌特定存活率乳腺癌特定存活率乳腺保护手术是什么?总体生存率总体生存率辐射疗法辐射疗法

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