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Updated: Jul 20, 2025

A Simplified and Efficient Method to Isolate Primary Human Keratinocytes from Adult Skin Tissue
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A Simplified and Efficient Method to Isolate Primary Human Keratinocytes from Adult Skin Tissue

Published on: August 25, 2018

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PP2A-B55alpha通过对Desmoplakin C-terminus的脱化来控制角质细胞粘附

Abbey L Perl1, Jennifer L Koetsier1, Kathleen J Green2,3,4

  • 1Department of Pathology, Feinberg School of Medicine, Northwestern University, 303 E Chicago Ave., Chicago, IL, 60611, USA.

Scientific reports
|August 5, 2023
PubMed
概括

蛋白质酸酶2A (PP2A) -B55α调节了脱莫巴林 (DP) 酸化,这对皮肤细胞粘附至关重要. 这一发现确定了维持表皮完整性和潜在治疗点的关键参与者.

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