机械通风后重症监护室的缺食症预测模型:系统性审查和元分析
Juan Chen1, Guangyu Lu2, Zhiyao Wang3,4
1School of Nursing and Public Health, Yangzhou University, Yangzhou, China.
The Laryngoscope
|August 6, 2023
概括
在重症监护病房 (ICU) 中的缺食症预测模型往往缺乏外部验证,并显示出高偏差. 关键预测因素包括延长内管和胃管的持续时间,以及高的APACHE II分数.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 胃肠病学 胃肠病学
背景情况:
- 缺食症是重症监护室 (ICU) 患者的关键病症,需要机械通风,可能导致死亡.
- 现有的关于ICU中缺食症预测因子的研究缺乏一致性,需要进行全面的审查.
研究的目的:
- 为了确定ICU患者在侵入性机械通风中出现食障碍的预测因素.
- 总结现有的风险预测模型,用于ICU的输出管外术后消化不良.
主要方法:
- 在五个主要数据库中进行了系统的文献搜索.
- 包括的研究为ICU患者开发了输出管外术后食障碍风险预测模型.
- 使用PROBAST进行了对个别预测变量和偏差风险评估的元分析.
主要成果:
- 包括九项研究,确定关键预测因素:内管持续时间 (≥72小时),APACHE II评分 (≥15),年龄 (≥65岁) 和胃管持续时间 (≥72小时).
- 普罗巴斯特分析表明,由于缺乏外部验证和方法限制,现有模型存在高偏差风险.
结论:
- 目前在ICU中的食障碍预测模型容易产生偏见,并且需要在不同患者群体中进行外部验证.
- 未来的研究应该优先考虑外部验证,并评估这些模型的临床实用性和接受性.
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