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在牛呼吸道疾病综合体中,七段性流感病毒的流行率和特征
Tirth Uprety1, Chithra C Sreenivasan1, Milton Thomas2
1Maxwell H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546, USA.
Virology
|August 6, 2023
概括
流感C (ICV) 和D (IDV) 病毒在患有牛呼吸道疾病 (BRD) 的牛中很常见. 这项研究发现,这两种病毒在BRD病例中普遍存在,突出了它们在牛肺炎中的作用.
科学领域:
- 兽医病毒学 兽医病毒学
- 动物传染病 动物传染病
- 分子流行病学分子流行病学
背景情况:
- 牛呼吸道疾病 (BRD) 综合体是牛病发和死亡的重要原因.
- 在受BRD感染的牛群中检测到C型流感病毒 (ICV) 和D型流感病毒 (IDV).
- 在患病的牛群中,ICV和IDV的分子流行病学和流行程度尚不清楚.
研究的目的:
- 为了调查ICV和IDV的流行率和分子特征在牛中与BRD.
- 确定ICV和IDV与牛肺炎病例的关联.
- 分析孤立的IDV菌株的抗原分歧.
主要方法:
- 从肺炎病例中对208个牛肺样本进行分子查.
- 使用分子技术检测ICV和IDV.
- 孤立的IDV菌株的遗传学和抗原分析.
主要成果:
- 在BRD病例中发现ICV和IDV都很普遍.
- 整体阳性率为IDV的20.88%和ICV的5.99%.
- 隔离的IDV菌株属于D/Michigan/2019类,并且显示出与流通中的主导类的抗原差异.
结论:
- IDV和ICV与牛中的BRD复合物有关.
- 这些病毒可能在牛呼吸道疾病的病因学中发挥作用.
- 进一步研究牛群中IDV和ICV的病原和控制是有必要的.
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