晚餐时间与中国农村葡萄糖代谢之间的关联:一项大规模的横截面研究
Kaiyang Zhang1, Yinhua Feng1, Yuanyuan Chai1
1College of Public Health, Zhengzhou University, Zhengzhou, China.
晚些时候的晚餐时间与改善葡萄糖代谢有关,显示更低的禁食胰岛素和胰岛素耐药性. 这种关联在年轻人中是显著的,但随着年龄的增长而减少.
科学领域:
- 代谢性疾病研究研究.
- 人口健康研究 人口健康研究
- 葡萄糖代谢和时代生物学
背景情况:
- 饮食时间是代谢健康的关键决定因素.
- 饮食时间的干扰与代谢疾病的风险增加有关.
- 了解晚餐时间对葡萄糖代谢的影响对于公共卫生至关重要.
研究的目的:
- 调查晚餐时间与葡萄糖代谢的关键标志物之间的关联.
- 为了评估中国农村人口之间的关系,在新陈代谢研究中经常代表性不足的人口.
- 探索潜在的剂量反应关系和与年龄相关的相互作用.
主要方法:
- 对来自中国农村群体的7701名参与者的横截面研究.
- 通过面对面调查问卷收集的数据.
- 多重线性回归和受限立方线用于分析晚餐时间,禁食胰岛素 (FINS),禁食血葡萄糖 (FPG) 和对胰岛素抵抗的恒温模型评估 (HOMA-IR).
主要成果:
- 晚餐时间延迟与较低的FINS (0.482 mmol/L每小时延迟) 和HOMA-IR (0.122 mmol/L每小时延迟) 显著相关.
- 随着晚餐时间的推迟,观察到FINS和HOMA-IR价值下降的明显趋势.
- 年龄和晚餐时间之间的相互作用显著影响了FINS和HOMA-IR,在69岁之前,这种关联是显著的.
结论:
- 在中国农村成年人中,晚餐时间和葡萄糖代谢之间存在显著的联系.
- 晚些时候的晚餐时间似乎是有益的,可能会降低禁食胰岛素水平.
- 晚餐时间对胰岛素耐药性的影响取决于年龄,在老年人中变得不那么明显.
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