经过导管大动脉置换后的急性冠心综合征
Milorad Zivkovic1, Sara Tomovic2, Ivan Busic2
1Cardiology Clinic, University Clinical Center of Serbia, Belgrade, Serbia.
Current problems in cardiology
|August 6, 2023
概括
过导管大动脉置换 (TAVR) 后的急性冠状动脉综合征 (ACS) 有独特的原因和较差的结果. 本综述检查了TAVR患者的ACS发病率,机制和治疗.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心血管研究研究心血管研究
背景情况:
- 通过导管的大动脉置换 (TAVR) 越来越多地用于年轻,风险较低的患者,导致更长的生存期.
- 在TAVR后的预期寿命延长增加了未来急性冠状动脉事件 (ACS) 的风险.
- 在TAVR患者中的ACS在临床上不同于非TAVR人群,具有独特的潜在机制.
研究的目的:
- 审查目前关于ACS发生率,时间和TAVR后的机制的数据.
- 分析以前经过TAVR手术的患者中ACS的原因.
- 检查TAVR患者中ACS的最佳侵入性治疗策略和临床结果.
主要方法:
- 对研究TAVR后ACS的综合文献综述.
- 在TAVR接受者中分析报告的ACS发病率,时间和病因因素.
- 评估治疗方法和短期和长期结果.
主要成果:
- 斑块破裂是ACS的主要原因,但非动脉血性机制 (栓塞,门阻塞) 在TAVR患者中更为频繁.
- 患有 ACS 的 TAVR 患者较少接受侵入性治疗.
- 在TAVR患者中,ACS与更糟糕的预后,更高的死亡率和增加主要不良心血管事件 (MACE) 有关.
结论:
- 在TAVR之后的ACS是一个研究不足但重要的临床问题,具有独特的特征和糟糕的结果.
- 了解TAVR后的ACS独特机制对于开发有效的管理策略至关重要.
- 需要进一步的研究来优化治疗和改善TAVR患者经历ACS的预后.
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