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Updated: Jul 20, 2025

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在B系细胞中具有双重功能的染色体组织者特殊的A-T丰富结合蛋白1

Morgane Thomas1,2, Charlotte Bruzeau1, Ophélie Alyssa Martin1

  • 1Laboratoire Contrôle de la Réponse Immune B et des Lymphoproliférations (CRIBL), Université de Limoges, CNRS Unité Mixte de Recherche 7276, Inserm Unité 1262, Limoges, France.

Cellular & molecular immunology
|August 6, 2023
PubMed
概括

特别的富A-T结合蛋白1 (SATB1) 不是B细胞发育必不可少的,但在成熟的B细胞中起着双重作用. SATB1调节免疫球蛋白基因转录,并在生殖中心反应期间限制体质突变.

关键词:
这是一个充满矛盾的环境.B 细胞 B 细胞 B 细胞核因素是一个核因素.身体上的超变异性突变.

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