在瘤学参考医院住院的患有癌症儿童的感染:一个横截面研究
Jonas Fernandes Vieira Filho1, Viviane Nunes Ribeiro1, Ábia Mariane Aquino do Nascimento1
1Instituto de Ensino, Pesquisa e Inovação, Liga Norte Riograndense Contra o Câncer Hospital, Natal, Rio Grande do Norte, Brazil.
Current microbiology
|August 6, 2023
概括
儿科瘤学患者面临高感染风险,血液恶性病如急性淋巴性白血病是常见的. 多种耐药性细菌,如大肠杆菌,是普遍存在的,需要针对性的感染控制策略.
科学领域:
- 儿科瘤学 儿科瘤学
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 儿科瘤患者由于癌症和治疗而免疫受损,增加感染易感性.
- 感染是接受癌症治疗的儿童患病和死亡的主要原因.
- 了解当地的感染特征对于有效管理至关重要.
研究的目的:
- 为了确定巴西一家参考医院的儿科瘤患者的感染概况.
- 识别常见的病原体和抗菌素耐药性模式.
- 分析与感染发生相关的因素.
主要方法:
- 2018-2021年住院儿科瘤患者的回顾性,横截面研究.
- 收集有关感染发作,患者人口统计,癌症类型和微生物学数据.
- 统计分析以确定与感染相关的因素 (p < 0.05).
主要成果:
- 在96名患者中确定了168次感染发作.
- 血液性恶性瘤 (62.4%),特别是急性淋巴性白血病 (74.6%),是最常见的.
- 大肠杆菌是主要的病原体 (31.9%),其中52%的分离物是多药耐药的.
- 过去30天的化疗,性别和癌症类型与感染风险有关.
结论:
- 这项研究强调了巴西儿科瘤患者的感染负担很大,包括多抗药生物体.
- 这些发现强调了疫情监测和量身定制的感染控制协议的必要性.
- 进一步的研究和基于证据的战略的实施对于减少与感染有关的并发症至关重要.
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