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慢性病中的高卡利米亚:专注于降低的药物治疗
Erasmia Sampani1, Marieta Theodorakopoulou1, Fotini Iatridi1
1Department of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Expert opinion on pharmacotherapy
|August 6, 2023
概括
超血症在慢性病 (CKD) 中很常见. 较新的结合剂,帕特和--环酸盐,有效地管理高血症,耐受性良好,允许继续使用必要的心脏和保护药物.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 心脏病学 心脏病学
- 内分泌学 在内分泌学.
背景情况:
- 超血是慢性病 (CKD) 的常见并发症,增加了发病率和死亡率.
- 对于心脏和脏保护至关重要的氨酸- ангиотензин- алдостерон系统阻断剂的使用通常受到高血症的限制.
- 现有的高血症治疗方法在长期疗效和安全性数据方面存在局限性.
研究的目的:
- 审查影响平衡的因素.
- 讨论用于治疗慢性病患者的高血症的新型治疗剂.
- 评估新的高血症治疗方法的疗效和安全性.
主要方法:
- 在PubMed/MEDLINE和Scopus数据库中进行全面的文献搜索,截至2023年4月.
- 对新保护疗法和高血症治疗的临床试验数据的分析.
- 对管理的既定和新兴药物的审查.
主要成果:
- 新的药物,如/葡萄糖携运输体-2 抑制剂和矿物质皮质糖类受体对抗剂,在脏保护方面表现有前途.
- 帕蒂罗默和 - 基 - 环酸盐是有效的口服结合剂,用于患有高血症的成年人.
- 这些新型药物表现出良好的耐受性和安全性,使RAAS抑制剂的持续使用成为可能.
结论:
- 新型结合剂提供了一种安全有效的策略,用于管理慢性病中的高血症.
- 改善高血症控制有助于使用心脏保护和脏保护疗法.
- 这些进步代表了管理CKD并发症的显著改进.
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