变异的正视镜镜片治疗区 (VOLTZ) 研究:一个为期2年的随机临床试验
Biyue Guo1, Sin Wan Cheung1, Randy Kojima2
1Centre for Myopia Research, School of Optometry, The Hong Kong Polytechnic University, Kowloon, Hong Kong SAR, China.
概括
带有较小背光区直径 (BOZD) 的正视镜 (ortho-k) 镜片导致两岁以上儿童的治疗区域 (TZ) 较小,轴延伸 (AE) 较少. 这些发现表明,BOZD影响了近视控制有效性.
科学领域:
- 眼科医生 眼科 眼科
- 视光学测量 视光学测量 视光学测量
- 儿科眼科护理 儿科眼科护理
背景情况:
- 脊椎病理学 (ortho-k) 是一种近视控制方法,使用一夜穿戴的刚性气体透透镜.
- 镜头设计参数,如后光区直径 (BOZD),可能会影响治疗结果.
- 了解这些参数对于优化儿童近视管理策略至关重要.
研究的目的:
- 为了比较两个年来穿着6mm或5mmBOZD正方形眼镜的儿童的轴延长 (AE) 和治疗区 (TZ) 特性.
- 为了研究透镜设计和近视控制治疗期间眼睛变化之间的关系.
主要方法:
- 一项随机研究涉及45名近视儿童 (6至11岁以下) 来自中国族裔.
- 参与者被分配使用6毫米或5毫米BOZD ortho-k镜头.
- 关于轴延长,治疗区域直径和胸膜厚度的数据在基线和每六个月收集一次,持续两年.
主要成果:
- 与6mm BOZD镜头 (水平:3.84mm,垂直:3.42mm) 相比,具有5mm BOZD的镜头产生了明显较小的TZ直径 (水平:2.69mm,垂直:2.65mm).
- 穿着5毫米BOZD镜头的受试者在24个月后,与穿着6毫米BOZD镜头 (0.35毫米) 的受试者相比,轴延长 (0.15毫米) 显著减少.
- 胸膜厚度的变化是暂时的,与AE的关联非常弱,这表明其他因素对减少AE的影响更大.
结论:
- 较小的BOZD ortho-k镜头导致较小的TZ直径,并且与两岁以上儿童的轴延伸减少有关.
- 这些发现表明,BOZD是对ortho-k治疗近视控制有效性的关键因素.
- 冠状腺厚度的变化似乎在观察到的轴延长减少中起到最小的作用.
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