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在小儿固体瘤幸存者的人类测量结果
Mehak Sehgal1, Vishesh Jain1, Sandeep Agarwala1
1Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India.
Nutrition and cancer
|August 7, 2023
概括
儿童癌症幸存者随着时间的推移显示营养状况有所改善. 然而,一些儿童经历了持续的营养不良,这凸显了持续监测和支持的必要性.
科学领域:
- 儿科瘤学 儿科瘤学
- 营养科学 营养科学
- 增长和发展 增长和发展
背景情况:
- 营养状况显著影响儿童癌症的结果和生存率.
- 儿童固体瘤幸存者的长期人体测量数据对于理解生长轨迹至关重要.
研究的目的:
- 为了评估长期人类测量结果在儿童固体瘤幸存者的队列.
- 评估从诊断到长期随访的营养状况的变化.
主要方法:
- 对317名小儿固体瘤幸存者的回顾性分析 (肝细胞母细胞瘤,恶性生殖细胞瘤,威尔姆斯瘤) 在1994-2016年期间接受治疗.
- 人类测量测量 (体重与年龄,身高与年龄,BMI与年龄的z-scores) 在诊断,治疗结束和最后的随访时收集.
- 增长z-scores是使用WHO和印度儿科学院的增长图表计算的;BMI评估了成年幸存者.
主要成果:
- 整体队列和个别瘤类型 (HB,MGCT,WT) 显示了从诊断到最后的随访后的人类测量趋势的改善.
- 在不同时间点之间观察到营养状况的统计学上显著改善.
- 尽管总体情况有所改善,但43%的成年幸存者体重不足,长期随访时,高达15%的儿童仍然营养不良.
结论:
- 在随访期间,人类测量措施通常会改善儿科固体瘤幸存者的情况.
- 显著的百分比的幸存者,无论是儿童还是成年人,经历持续的营养不良,强调需要持续的营养监测.
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