乌克兰SARS-CoV-2感染儿童的流行病学,临床和实验室特征
Tetiana Harashchenko1, Tetiana Umanets1, Volodymyr Podolskiy1
1Department of Respiratory Diseases and Allergy in Children, SI "Institute of Pediatrics, Obstetrics and Gynecology named after Academician O.M. Lukyanova, National Academy of Medical Sciences of Ukraine", Kyiv, Ukraine.
Journal of mother and child
|August 7, 2023
概括
乌克兰儿童的COVID-19通常表现为中度疾病,其特点是发烧,喉疼痛和咳. 大多数住院的儿科患者康复良好,尽管严重的病例显示呼吸困难和肺部异常.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 由SARS-CoV-2引起的COVID-19大流行,最初导致人们误以为儿童是免疫的.
- 新出现的证据证实了所有年龄组的易感性,需要对儿科COVID-19病例进行研究.
研究的目的:
- 调查乌克兰诊断出COVID-19的住院儿童的临床和流行病学特征.
- 了解疾病的进展,并确定儿科患者的风险因素.
主要方法:
- 对171名确诊感染SARS-CoV-2的儿科患者 (2个月至18岁) 进行了回顾性分析.
- 收集的数据包括症状,疾病严重程度,并发症,实验室结果 (CRP) 和放射性发现.
主要成果:
- 大多数儿童 (77.78%) 患有中度的COVID-19,而22.22%患有严重的疾病. 发烧 (88.2%),喉痛 (69.2%) 和咳 (60.9%) 是最常见的症状.
- 6-12岁的儿童是受影响最严重的群体. 严重的病例与呼吸障碍和蓝色症有关 (p<0.05).
- 慢性桃体炎和贫血等并发症很常见. 升高的CRP水平与疾病严重程度相关 (r=0.7,p<0.05). 肺部X射线变化,包括地面玻璃的不透明性,在很大一部分患者中观察到.
结论:
- 住院的乌克兰儿童的COVID-19通常遵循中度的过程.
- 乌克兰儿童COVID-19患者的预后通常是有利的,尽管存在并发症和放射性发现.
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