对于患有上道尿路癌的患者来说,这是一个生存模式
Chengliang Sun1, Xuewu Zhou2, Jiangyong Lou3
1Department of Urology, Wuchang Hospital Affiliated to Wuhan University of Science and Technology, 430063 Wuhan, Hubei, China.
Archivos espanoles de urologia
|August 7, 2023
概括
一个新的诺莫格拉姆模型预测了上道泌尿道癌 (UTUC) 患者的死亡风险. 该工具有助于制定个性化治疗计划,以改善生存结果.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 在瘤学瘤学.
- 医学统计 医学统计
背景情况:
- 上道泌尿道癌 (UTUC) 是一种罕见的恶性瘤.
- 准确的预后模型对于患者管理至关重要.
研究的目的:
- 开发和验证UTUC患者的生存预测模型.
- 确定术后死亡的独立风险因素.
主要方法:
- 对241名UTUC患者 (2010-2018) 的回顾性分析.
- 多变量物流回归用于识别风险因素.
- 使用ROC和校准曲线构建和验证Nomogram.
主要成果:
- 年龄较大,瘤直径较大,等级较高,晚期和缺乏化疗与死亡率有关.
- 高度瘤,尿管位置,大直径,高病态阶段和淋巴结转移是独立的风险因素.
- 命名图表显示出良好的区分 (AUC=0.828) 和校准.
结论:
- 开发的诺米图有效预测UTUC的死亡风险和术后存活率.
- 该模型支持个性化的治疗策略,以提高患者的预后.
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