儿童中COVID-19的长期中枢神经系统 (CNS) 后果
Saskia Howe de la Torre1, Valeria Parlatini2, Samuele Cortese1,3,4,5
1School of Psychology, University of Southampton, Southampton, UK.
Expert review of neurotherapeutics
|August 7, 2023
概括
长期COVID经常导致儿童的神经和神经精神症状,包括头痛和疲劳. 需要更多的研究来了解患病率,并开发有效的治疗方法来治疗这些令人衰弱的长期COVID影响.
科学领域:
- 儿科神经学 儿科神经学
- 神经精神病学是一种神经精神病学.
- 传染病流行病学 传染病流行病学
背景情况:
- 长期COVID (SARS-CoV-2感染的急性后续) 在儿童和年轻人中呈现出各种神经/神经精神症状.
- 常见的症状包括头痛,疲劳,认知缺陷,厌氧/衰老,头,情绪障碍和睡眠问题.
- 由于研究异质性,样本规模小,随访时间短,现有的患病率估计是高度可变的.
研究的目的:
- 在儿童群体中全面审查长期COVID的神经和神经精神表现.
- 专注于症状发病率,相关的人口特征和潜在的病原遗传机制.
- 突出进一步研究的必要性,以支持临床认可和指导未来的治疗策略.
主要方法:
- 文献综述和现有关于儿科长期COVID的研究的综合.
- 报告的神经和神经精神症状及其患病率的分析.
- 讨论潜在的潜在机制和促成因素.
主要成果:
- 神经/神经精神症状经常在长期COVID患者的儿童和年轻人中观察到.
- 患病率数据不一致,需要进行更大规模的研究,随访时间更长.
- 遗传学,种族和并发症等研究较少的风险因素需要进一步调查.
结论:
- 持续的神经/神经精神症状可以显著影响儿童的日常功能和福利后SARS-CoV-2感染.
- 澄清病原遗传机制对于开发向治疗至关重要.
- 强化查计划和精神教育建议用于早期识别和管理儿科长期COVID神经/神经精神疾病.
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