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用电子注射装置分析生长激素注射日志,以确定对低刺激剂配方的坚持,并探索对坚持有影响的因素

Kei Takasawa¹, Hiroyo Mabe², Fusa Nagamatsu²

¹Department of Pediatrics and Developmental Biology, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

Patient preference and adherence

|August 7, 2023

概括

电子生长激素注射装置可以识别接受生长激素治疗 (GHT) 的儿童的坚持问题. 不规则的注射时间表,如午夜后发生的注射时间表,显著影响了坚持率,突出了对个性化方法的需求.

科学领域:

儿科儿科儿科
内分泌学在内分泌学.
数字健康数字健康

背景情况:

在长期生长激素治疗 (GHT) 中,治疗的成功取决于患者的坚持.
在接受GHT的儿童中,报告了坚持 (7-71%不坚持) 的显著变化.
数字健康技术为准确的GHT合规性评估提供了潜力.

研究的目的:

用电子GH注射装置评估对GHT的坚持.
为了探索影响儿童患者接受GHT的坚持因素.
评估数字健康工具在监测GHT遵守方面的实用性.

主要方法:

这是一项多中心的回顾性队列研究,涉及41名身材矮小的儿科患者.
使用电子GH注射装置 (GROWJECTOR®L) 在12-48周内进行日志分析.
通过智能手机和云服务器收集的注射日志数据,以获得合规资格.

主要成果:

总体累积依从性超过95%,但12.2%的患者表现出低依从性 (<85%).
自我选择的GH装置和不规则的注射时间表 (例如,午夜后) 显著影响了坚持 (p=0.034,p=0.048).
较高的不规则注射率与较低的坚持相关 (p=0.029).

结论:

电子GH设备可以检测影响粘附性的不规则注射模式.
数字工具促进了协作监测,并加强了GHT中的患者自主权.
与数字设备相结合的个性化方法可以改善和维持GHT的坚持.

关键词:

对于GH的治疗,GH疗法是一种治疗.数字健康技术数字健康技术患者的自主权患者的自主权共享决策 - - 分享决策.

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