认知障碍可以预测痴呆症的行为和心理症状
Solaphat Hemrungrojn1,2, Sookjaroen Tangwongchai1,3, Thammanard Charernboon4
1Department of Psychiatry, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, the Thai Red Cross Society, Bangkok, Thailand.
Frontiers in neurology
|August 7, 2023
概括
泰国神经精神病查询问卷 (NPI-Q) 有效地选痴呆症 (BPSD) 的行为和心理症状. 认知缺陷与BPSD得分相关,这表明aMCI患者有严重症状可能会发展为痴呆症.
科学领域:
- 神经学 神经学
- 老年病的医生 老年病的医生
- 精神病学是一个精神病学.
背景情况:
- 痴呆症的行为和心理症状 (BPSD) 在阿尔茨海默病中很常见.
- 准确的查工具对于早期发现和管理BPSD至关重要.
- 轻度认知障碍 (MCI) 可能是痴呆症的先兆,而 BPSD 可能是早期的指标.
研究的目的:
- 验证泰国版本的神经精神科目录问卷 (NPI-Q) 作为BPSD的查工具.
- 为了研究认知功能和BPSD之间的关联,在有amnestic轻度认知障碍 (aMCI) 和阿尔茨海默氏症类型痴呆症 (DAT) 的个体中.
主要方法:
- 120名参与者 (80名MCI,40名DAT) 和他们的护理人员被录取.
- 泰国NPI-Q和神经精神科目录 (NPI) 进行了管理.
- 用蒙特利尔认知评估 (MoCA) 评估认知表现.
主要成果:
- 泰国NPI-Q证明了BPSD查的良好有效性和可靠性.
- 在aMCI/DAT和DAT组组合的MoCA得分和NPI-Q得分之间观察到显著的负相关性.
- 集群分析发现了一个独特的"DAT + BPSD"组,包括50%的DAT患者.
结论:
- 在泰国老年人群中,NPI-Q是评估BPSD的合适工具.
- 认知障碍显著预测了BPSD严重程度.
- 在aMCI患者中,严重的BPSD可能表明进展为痴呆症的风险更高.
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