超越CPAP:修改上呼吸道输出用于治疗OSA
Eli Gruenberg1, Jessica Cooper1, Tania Zamora2
1Division of Pulmonary, Critical Care, and Sleep Medicine, University of California, San Diego, La Jolla, CA, United States.
Frontiers in neurology
|August 7, 2023
概括
除了CPAP之外的阻塞性睡眠呼吸暂停 (OSA) 治疗由于治疗限制至关重要. 本综述探讨了其他方法,重点是修改OSA管理的上呼吸道肌肉行为.
科学领域:
- 睡眠医学 睡眠医学
- 呼吸系统医学 呼吸系统医学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是一种普遍的疾病,经常未得到充分治疗.
- 持续正气道压力 (CPAP) 是标准的OSA疗法,但面临着坚持和可用性的挑战.
- 2021年全球CPAP短缺强调了需要替代OSA治疗策略的需要.
研究的目的:
- 审查针对阻塞性睡眠呼吸暂停 (OSA) 的治疗方法,重点是修改上呼吸道肌肉行为.
- 为突出持续正气道压力 (CPAP) 治疗的替代方案.
- 讨论各种上呼吸道肌肉训练技术的有效性和应用.
主要方法:
- 对现有研究和临床实践的文献综述.
- 对OSA的非CPAP治疗方式的分析.
- 根据作用机制对治疗进行分类,重点关注上呼吸道肌肉行为改变.
主要成果:
- 其他OSA疗法包括定位疗法,下前进装置和上呼吸道手术.
- 上呼吸道训练包括运动,神经肌肉电刺激和弹风乐器.
- 更多的侵入性选择,如低分泌神经刺激装置也可用.
结论:
- 修改上呼吸道肌肉行为为OSA管理提供了一个有前途的治疗途径.
- 考虑CPAP替代品的个性化方法对于有效的OSA治疗至关重要.
- 对上呼吸道肌肉训练有效性的进一步研究是有必要的.
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