心率变化在不明原因昏迷患者与健康对照:一项比较研究
Rashmi R Dash1, Priyadarsini Samanta1, Susnato Das1
1Department of Physiology, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus
|August 7, 2023
概括
无法解释的昏迷患者表现出心率变化 (HRV) 的改变,表明交感神经系统占主导地位. 这一发现可能有助于早期诊断和对昏发作进行干预.
科学领域:
- 心脏病学 心脏病学
- 自主神经系统功能 自主神经系统功能
背景情况:
- 昏迷或昏是暂时失去意识,这可能表明心脏事件的死亡风险增加.
- 心率变化 (HRV) 评估自主功能,并可能揭示昏迷患者的异常.
- 了解昏睡的自主变化对于早期诊断和干预至关重要.
研究的目的:
- 为了比较患有不明原因昏迷的患者和年龄相匹配的健康对照之间的HRV参数.
- 调查HRV参数与脉冲和血压等心血管指标之间的相关性.
主要方法:
- 在25例昏迷病例和25例对照患者中记录了5分钟的心电图 (ECG).
- 用ADInstruments的PowerLab.com进行了心率变化 (HRV) 分析.
- RR间隔的标准偏差 (SDRR) 和LF/HF比率是分析的关键HRV指标.
主要成果:
- 与对照组 (71.27 ± 27.40 ms) 相比,昏迷患者的SDRR平均值 (21.93 ± 3.53 ms) 显著降低.
- 低频与高频 (LF/HF) 的比率在昏迷病例中显著高 (1.43 ± 0.40) 比对照组 (0.98 ± 1.07).
- 在HRV测量和脉冲或平均血压之间没有发现显著的相关性.
结论:
- 研究结果表明,在经历不明原因昏迷的人中,交感神经系统占主导地位.
- 在昏迷患者中改变的HRV参数突出显示了潜在的自主功能障碍.
- 这些HRV变化可以作为生物标志物来识别风险.
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