一个Rosai-Dorfman疾病病例呈现为一个孤立的肺斑
Arun Rathinam1, Sushan Gupta1, Rukhsaar Khanam1
1Internal Medicine, Carle Foundation Hospital, Urbana, USA.
Cureus
|August 7, 2023
概括
罗莎伊-多夫曼病 (RDD) 是一种罕见的囊细胞性疾病,可以呈现为孤立的多质群. 这一病例突显出一种独特的肺部表现,并表明观察可能适用于无症状病例.
科学领域:
- 病理学 病理学 病理学
- 肺部病理学 肺部病理学
- 在瘤学瘤学.
背景情况:
- 罗莎-多夫曼病 (RDD) 是一种罕见的非朗格汉斯基质细胞性疾病,通常影响淋巴结.
- 外节性RDD呈现异质,孤立的肺部参与不常见.
研究的目的:
- 报告第一个记录的RDD病例,呈现为孤立的肺部质量.
- 讨论这种罕见表现的诊断和管理影响.
主要方法:
- 一个55岁的女性的病例报告,胸部疼痛和扩大的肺病变.
- 胸腔质量的手术切除.
- 通过免疫组织化学的组织病理学检查 (CD1a阴性,S100阳性,皮病).
主要成果:
- 组织病理学证实了RDD与非典型的囊细胞透和原纤维化.
- 免疫组织化学检测结果对S100呈阳性,对CD1a呈阴性,并观察到emperipolesis.
- 六个月后,在CT监测中,患者仍然没有复发.
结论:
- 隔离性肺部质量是一种罕见但可能出现的Rosai-Dorfman疾病.
- 这一案例强调了考虑RDD在多发性损伤差异诊断中的重要性.
- 积极监测可能是一个无症状的可行的选择,隔离的多发性RDD.
相关概念视频
Pleural Disorders: Types and Brief Description
235
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
235
Pleural Effusion I: Introduction
1.2K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
1.2K
Rous Sarcoma Virus (RSV) and Cancer
5.1K
Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...
5.1K
Endocarditis II: Clinical Features of Infective Endocarditis
14
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
14
Rheumatic Heart Disease I: Introduction
16
Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
16
Pleura of the Lungs
2.1K
The lungs are nestled in a cavity, shielded by the pleura. The pleura, a form of serous membrane, wraps around each lung. This membrane arrangement consists of two layers: the visceral and parietal pleurae. The visceral pleura lines the surface of the lungIn contrast, the parietal pleura is the outer layer and contacts to the thoracic wall, the mediastinum, and the diaphragm. The hilum is the point of connection between the visceral and parietal layers. The space between the parietal and...
2.1K


