基于亲属信息的堆叠合集可以预测混合性能,其准确性与基于标记器的GBLUPUP相比
Philipp Georg Heilmann1, Matthias Frisch1, Amine Abbadi2
1Institute of Agronomy and Plant Breeding II, Justus Liebig University, Gießen, Germany.
Frontiers in plant science
|August 7, 2023
概括
机器学习,特别是堆叠的梯度增强机组,可以在不平衡的育种数据中改善混合性能预测. 这种方法,使用亲属信息,显示了提高植物育种计划的选择效率的希望.
科学领域:
- 农业科学 农业科学
- 遗传学 是一个遗传学.
- 计算生物学 计算生物学
背景情况:
- 杂交育种计划经常面临不平衡和不完整的测试交叉数据的挑战.
- 特殊组合能力 (SCA) 可以主导一般组合能力 (GCA),降低基于GCA的选择效率.
研究的目的:
- 将机器学习算法的预测精度与基于GCA的预测和基因组最佳线性无偏预测 (GBLUP) 进行比较.
- 在不平衡的因子数中使用父系,混合性能和基因型标记数据来评估机器学习性能.
主要方法:
- 调查了六个不平衡的,不完整的植物因子,来自油菜种子,小麦和玉米杂交育种计划.
- 应用各种机器学习算法,包括堆叠的梯度增强机组合.
- 使用了亲属信息,混合性能数据和基因型标记数据作为预测变量.
主要成果:
- 基于亲属信息的堆叠组合在两个高度不平衡的菜种子因数中超过了GCA预测.
- 在这些情况下,预测准确度从0.39增加到0.45和0.48增加到0.54.
- 机器学习模型实现了与GBLUP相比的预测准确性,即使不需要标记数据.
结论:
- 使用亲属信息的梯度增强机器的堆叠组合为混合预测提供了一个有希望的策略.
- 这种方法在具有高SCA差异的数据集中尤其有价值,提高了选择效率.
- 需要对各种数据集进行进一步的研究,以确认该方法的广泛适用性.
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